Oxidative stress impairs the Nur77‐Sirt1 axis resulting in a decline in organism homeostasis during aging

Sirt1 is an NAD(+)‐dependent deacetylase that protects against premature aging and cell senescence. Aging accompanied by oxidative stress leads to a decrease in Sirt1 levels and activity, but the regulatory mechanism that connects these events remains unclear. Here, we reported that Nur77, which sha...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Song, Xiaoyu, Wang, Xiaoxun, Zheng, Lixia, Ma, Guojing, Liu, Weiwei, Su, Han, Liu, Xiyan, Liu, Tingting, Cao, Liu, Wang, Difei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186606/
https://www.ncbi.nlm.nih.gov/pubmed/36883265
http://dx.doi.org/10.1111/acel.13812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186606/
https://www.ncbi.nlm.nih.gov/pubmed/36883265
http://dx.doi.org/10.1111/acel.13812

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