Cargando…

Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation

Age is the main risk factor for the development of neurodegenerative diseases. In the aged brain, axonal degeneration is an early pathological event, preceding neuronal dysfunction, and cognitive disabilities in humans, primates, rodents, and invertebrates. Necroptosis mediates degeneration of injur...

Descripción completa

Detalles Bibliográficos
Autores principales: Arrázola, Macarena S., Lira, Matías, Véliz‐Valverde, Felipe, Quiroz, Gabriel, Iqbal, Somya, Eaton, Samantha L., Lamont, Douglas J., Huerta, Hernán, Ureta, Gonzalo, Bernales, Sebastián, Cárdenas, J. César, Cerpa, Waldo, Wishart, Thomas M., Court, Felipe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186608/
https://www.ncbi.nlm.nih.gov/pubmed/36973898
http://dx.doi.org/10.1111/acel.13814