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Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation
Age is the main risk factor for the development of neurodegenerative diseases. In the aged brain, axonal degeneration is an early pathological event, preceding neuronal dysfunction, and cognitive disabilities in humans, primates, rodents, and invertebrates. Necroptosis mediates degeneration of injur...
Autores principales: | Arrázola, Macarena S., Lira, Matías, Véliz‐Valverde, Felipe, Quiroz, Gabriel, Iqbal, Somya, Eaton, Samantha L., Lamont, Douglas J., Huerta, Hernán, Ureta, Gonzalo, Bernales, Sebastián, Cárdenas, J. César, Cerpa, Waldo, Wishart, Thomas M., Court, Felipe A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186608/ https://www.ncbi.nlm.nih.gov/pubmed/36973898 http://dx.doi.org/10.1111/acel.13814 |
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