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Effect of peripheral cellular senescence on brain aging and cognitive decline

We examine similar and differential effects of two senolytic treatments, ABT‐263 and dasatinib + quercetin (D + Q), in preserving cognition, markers of peripheral senescence, and markers of brain aging thought to underlie cognitive decline. Male F344 rats were treated from 12 to 18 months of age wit...

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Detalles Bibliográficos
Autores principales: Budamagunta, Vivekananda, Kumar, Ashok, Rani, Asha, Bean, Linda, Manohar‐Sindhu, Sahana, Yang, Yang, Zhou, Daohong, Foster, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186609/
https://www.ncbi.nlm.nih.gov/pubmed/36959691
http://dx.doi.org/10.1111/acel.13817