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Senescence‐associated transcriptional derepression in subtelomeres is determined in a chromosome‐end‐specific manner

Aging is a continuous process leading to physiological deterioration with age. One of the factors contributing to aging is telomere shortening, causing alterations in the protein protective complex named shelterin and replicative senescence. Here, we address the question of the link between this tel...

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Detalles Bibliográficos
Autores principales: Rey‐Millet, Martin, Pousse, Mélanie, Soithong, Chan, Ye, Jing, Mendez‐Bermudez, Aaron, Gilson, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186611/
https://www.ncbi.nlm.nih.gov/pubmed/36924026
http://dx.doi.org/10.1111/acel.13804