SUMOylation of PDGF receptor α affects signaling via PLCγ and STAT3, and cell proliferation

BACKGROUND: The platelet-derived growth factor (PDGF) family of ligands exerts their cellular effects by binding to α- and β-tyrosine kinase receptors (PDGFRα and PDGFRβ, respectively). SUMOylation is an important posttranslational modification (PTM) which regulates protein stability, localization,...

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Detalles Bibliográficos
Autores principales: Wang, Kehuan, Papadopoulos, Natalia, Hamidi, Anahita, Lennartsson, Johan, Heldin, Carl-Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186711/
https://www.ncbi.nlm.nih.gov/pubmed/37193980
http://dx.doi.org/10.1186/s12860-023-00481-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186711/
https://www.ncbi.nlm.nih.gov/pubmed/37193980
http://dx.doi.org/10.1186/s12860-023-00481-6

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