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Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection

Although host responses to the ancestral SARS-CoV-2 strain are well described, those to the new Omicron variants are less resolved. We profiled the clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoires of >1,000 blood cell or plasma specimens from SARS-CoV-2 Omicron pa...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Liu, Cuicui, Xie, Xiaowei, Niu, Mingming, Wang, Yingrui, Cheng, Xuelian, Zhang, Biao, Zhang, Dong, Liu, Mengyao, Sun, Rui, Ma, Yezi, Ma, Shihui, Wang, Huijun, Zhu, Guoqing, Lu, Yang, Huang, Baiming, Su, Pei, Chen, Xiaoyuan, Zhao, Jingjing, Wang, Hongtao, Shen, Long, Fu, Lixia, Huang, Qianqian, Yang, Yang, Wang, He, Wu, Chunlong, Ge, Weigang, Chen, Chen, Huo, Qianyu, Wang, Qingping, Wang, Ying, Geng, Li, Xie, Yan, Xie, Yi, Liu, Lijun, Qi, Jianwei, Chen, Huaiyong, Wu, Junping, Jiang, Erlie, Jiang, Wentao, Wang, Ximo, Shen, Zhongyang, Guo, Tiannan, Zhou, Jiaxi, Zhu, Ping, Cheng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10186977/
https://www.ncbi.nlm.nih.gov/pubmed/37257450
http://dx.doi.org/10.1016/j.immuni.2023.05.007