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Copper Efflux System Required in Murine Lung Infection by Haemophilus influenzae Composed of a Canonical ATPase Gene and Tandem Chaperone Gene Copies

Copper is an essential micronutrient but is toxic at high concentrations. In Haemophilus influenzae mechanisms of copper resistance and its role in pathogenesis are unknown; however, our previous genetic screen by transposon insertion-site sequencing implicated a putative cation transporting ATPase...

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Detalles Bibliográficos
Autores principales: Wong, Sandy M., Gawronski, Jeffrey, Akerley, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187127/
https://www.ncbi.nlm.nih.gov/pubmed/37014212
http://dx.doi.org/10.1128/iai.00091-23