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Impaired microglia-mediated synaptic pruning in the nucleus accumbens during adolescence results in persistent dysregulation of familiar, but not novel social interactions in sex-specific ways

Evolutionarily conserved, peer-directed social behaviors are essential to participate in many aspects of human society. These behaviors directly impact psychological, physiological, and behavioral maturation. Adolescence is an evolutionarily conserved period during which reward-related behaviors, in...

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Detalles Bibliográficos
Autores principales: Kirkland, Julia M., Edgar, Erin L., Patel, Ishan, Kopec, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187149/
https://www.ncbi.nlm.nih.gov/pubmed/37205324
http://dx.doi.org/10.1101/2023.05.02.539115