Structural basis of the T4 bacteriophage primosome assembly and primer synthesis

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The T4 bacteriophage gp41 helicase and gp61 primase assemble into a primosome complex to couple DNA unwinding with RNA primer synthesis for DNA replication. How a primosome is assembled and how the length of the RNA primer is defined in the T4 bacteriophage, or in any model system, are unclear. Here...

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Detalles Bibliográficos
Autores principales: Feng, Xiang, Spiering, Michelle M., de Luna Almeida Santos, Ruda, Benkovic, Stephen J., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187150/
https://www.ncbi.nlm.nih.gov/pubmed/37205424
http://dx.doi.org/10.1101/2023.05.03.539249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187150/
https://www.ncbi.nlm.nih.gov/pubmed/37205424
http://dx.doi.org/10.1101/2023.05.03.539249

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