Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology

Recent structural studies show the Rad24-RFC loads the 9-1-1 checkpoint clamp onto a recessed 5′ end by binding the 5′ DNA on Rad24 at an external surface site and threading the 3′ ssDNA into the well-established internal chamber and into 9-1-1. We find here that Rad24-RFC loads 9-1-1 onto DNA gaps...

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Detalles Bibliográficos
Autores principales: Zheng, Fengwei, Georgescu, Roxana E., Yao, Nina Y., O’Donnell, Michael E., Li, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187155/
https://www.ncbi.nlm.nih.gov/pubmed/37205533
http://dx.doi.org/10.1101/2023.05.03.539266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187155/
https://www.ncbi.nlm.nih.gov/pubmed/37205533
http://dx.doi.org/10.1101/2023.05.03.539266

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