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Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification to biology
Recent structural studies show the Rad24-RFC loads the 9-1-1 checkpoint clamp onto a recessed 5′ end by binding the 5′ DNA on Rad24 at an external surface site and threading the 3′ ssDNA into the well-established internal chamber and into 9-1-1. We find here that Rad24-RFC loads 9-1-1 onto DNA gaps...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187155/ https://www.ncbi.nlm.nih.gov/pubmed/37205533 http://dx.doi.org/10.1101/2023.05.03.539266 |