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Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase

Protein function hinges on small shifts of three-dimensional structure. Elevating temperature or pressure may provide experimentally accessible insights into such shifts, but the effects of these distinct perturbations on protein structures have not been compared in atomic detail. To quantitatively...

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Detalles Bibliográficos
Autores principales: Guerrero, Liliana, Ebrahim, Ali, Riley, Blake T., Kim, Minyoung, Huang, Qingqiu, Finke, Aaron D., Keedy, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187168/
https://www.ncbi.nlm.nih.gov/pubmed/37205580
http://dx.doi.org/10.1101/2023.05.02.538097