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Pushed to extremes: distinct effects of high temperature vs. pressure on the structure of an atypical phosphatase
Protein function hinges on small shifts of three-dimensional structure. Elevating temperature or pressure may provide experimentally accessible insights into such shifts, but the effects of these distinct perturbations on protein structures have not been compared in atomic detail. To quantitatively...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187168/ https://www.ncbi.nlm.nih.gov/pubmed/37205580 http://dx.doi.org/10.1101/2023.05.02.538097 |