The lncRNA Neat1 is associated with astrocyte reactivity and memory deficits in a mouse model of Alzheimer’s disease

Dysregulation of long non-coding RNAs (lncRNAs) have been associated with Alzheimer’s disease (AD). However, the functional role of lncRNAs in AD remains unclear. Here, we report a crucial role for the lncRNA Neat1 in astrocyte dysfunction and memory deficits associated with AD. Transcriptomics anal...

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Detalles Bibliográficos
Autores principales: Irwin, Ashleigh B, Martina, Verdion, Jago, Silvienne C Sint, Bahabry, Rudhab, Schreiber, Anna Maria, Lubin, Farah D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187170/
https://www.ncbi.nlm.nih.gov/pubmed/37205548
http://dx.doi.org/10.1101/2023.05.03.539260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187170/
https://www.ncbi.nlm.nih.gov/pubmed/37205548
http://dx.doi.org/10.1101/2023.05.03.539260

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