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The lncRNA Neat1 is associated with astrocyte reactivity and memory deficits in a mouse model of Alzheimer’s disease
Dysregulation of long non-coding RNAs (lncRNAs) have been associated with Alzheimer’s disease (AD). However, the functional role of lncRNAs in AD remains unclear. Here, we report a crucial role for the lncRNA Neat1 in astrocyte dysfunction and memory deficits associated with AD. Transcriptomics anal...
Autores principales: | Irwin, Ashleigh B, Martina, Verdion, Jago, Silvienne C Sint, Bahabry, Rudhab, Schreiber, Anna Maria, Lubin, Farah D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187170/ https://www.ncbi.nlm.nih.gov/pubmed/37205548 http://dx.doi.org/10.1101/2023.05.03.539260 |
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