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High performance anion exchange chromatography purification of probiotic bacterial extracellular vesicles enhances purity and anti-inflammatory efficacy

Bacterial extracellular vesicles (BEVs), including outer membrane vesicles (OMVs), have emerged as a promising new class of vaccines and therapeutics to treat cancer and inflammatory diseases, among other applications. However, clinical translation of BEVs is hindered by a current lack of scalable a...

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Detalles Bibliográficos
Autores principales: Piroli, Nicholas H., Reus, Laura Samantha C., Mamczarz, Zuzanna, Khan, Sulayman, Bentley, William E., Jay, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187247/
https://www.ncbi.nlm.nih.gov/pubmed/37205369
http://dx.doi.org/10.1101/2023.05.01.538917