FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer

While oncogenes promote cancer cell growth, unrestrained proliferation represents a significant stressor to cellular homeostasis networks such as the DNA damage response (DDR). To enable oncogene tolerance, many cancers disable tumor suppressive DDR signaling through genetic loss of DDR pathways and...

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Detalles Bibliográficos
Autores principales: Menon, Shruti, Breese, Marcus R., Lin, Yone Phar, Allegakoen, Hannah, Perati, Shruthi, Heslin, Ann, Horlbeck, Max A., Weissman, Jonathan, Sweet-Cordero, E. Alejandro, Bivona, Trever G., Tulpule, Asmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187251/
https://www.ncbi.nlm.nih.gov/pubmed/37205599
http://dx.doi.org/10.1101/2023.04.30.538578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187251/
https://www.ncbi.nlm.nih.gov/pubmed/37205599
http://dx.doi.org/10.1101/2023.04.30.538578

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