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A Bayesian Noisy Logic Model for Inference of Transcription Factor Activity from Single Cell and Bulk Transcriptomic Data

The advent of high-throughput sequencing has made it possible to measure the expression of genes at relatively low cost. However, direct measurement of regulatory mechanisms, such as Transcription Factor (TF) activity is still not readily feasible in a high-throughput manner. Consequently, there is...

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Detalles Bibliográficos
Autores principales: Arriojas, Argenis, Patalano, Susan, Macoska, Jill, Zarringhalam, Kourosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187261/
https://www.ncbi.nlm.nih.gov/pubmed/37205561
http://dx.doi.org/10.1101/2023.05.03.539308