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CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation
BACKGROUND: The number and escape levels of genes that escape X chromosome inactivation (XCI) in female somatic cells vary among tissues and cell types, potentially contributing to specific sex differences. Here we investigate the role of CTCF, a master chromatin conformation regulator, in regulatin...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187265/ https://www.ncbi.nlm.nih.gov/pubmed/37205597 http://dx.doi.org/10.1101/2023.05.04.539469 |