CTCF-mediated insulation and chromatin environment modulate Car5b escape from X inactivation

BACKGROUND: The number and escape levels of genes that escape X chromosome inactivation (XCI) in female somatic cells vary among tissues and cell types, potentially contributing to specific sex differences. Here we investigate the role of CTCF, a master chromatin conformation regulator, in regulatin...

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Detalles Bibliográficos
Autores principales: Fang, He, Tronco, Ana R., Bonora, Giancarlo, Nguyen, Truong, Thakur, Jitendra, Berletch, Joel B., Filippova, Galina N., Henikoff, Steven, Shendure, Jay, Noble, William S., Disteche, Christine M., Deng, Xinxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187265/
https://www.ncbi.nlm.nih.gov/pubmed/37205597
http://dx.doi.org/10.1101/2023.05.04.539469

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