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Microglial synaptic pruning in the nucleus accumbens during adolescence sex-specifically influences splenic immune outcomes

Strong social support promotes a variety of positive health outcomes in humans and rodent models, while social isolation in rodents shortens lifespan, perceived social isolation (i.e. loneliness) can increase mortality by up to 50% in humans. How social relationships lead to these drastic health eff...

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Detalles Bibliográficos
Autores principales: Kirkland, J. M., Patel, Ishan, Ardeshna, Monali S., Kopec, Ashley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187280/
https://www.ncbi.nlm.nih.gov/pubmed/37205376
http://dx.doi.org/10.1101/2023.05.03.539317