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Direct androgen receptor regulation of sexually dimorphic gene expression in the mammalian kidney

Mammalian organs exhibit distinct physiology, disease susceptibility and injury responses between the sexes. In the mouse kidney, sexually dimorphic gene activity maps predominantly to proximal tubule (PT) segments. Bulk RNA-seq data demonstrated sex differences were established from 4 and 8 weeks a...

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Detalles Bibliográficos
Autores principales: Xiong, Lingyun, Liu, Jing, Han, Seung Yub, Koppitch, Kari, Guo, Jin-Jin, Rommelfanger, Megan, Gao, Fan, Hallgrimsdottir, Ingileif B., Pachter, Lior, Kim, Junhyong, MacLean, Adam L., McMahon, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187285/
https://www.ncbi.nlm.nih.gov/pubmed/37205355
http://dx.doi.org/10.1101/2023.05.06.539585