Critical role of down-regulated in adenoma bicarbonate transporter in linaclotide stimulated intestinal bicarbonate secretion

Duodenal bicarbonate secretion is critical to epithelial protection, nutrient digestion/absorption and is impaired in cystic fibrosis (CF). We examined if linaclotide, typically used to treat constipation, may also alter duodenal bicarbonate secretion. Bicarbonate secretion was measured in vivo and...

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Detalles Bibliográficos
Autores principales: Sarthi, Jessica B., Trumbull, Annie M., Abazari, Shayda M., van Unen, Vincent, Chan, Joshua E., Joo, Nam Soo, Jiang, Yanfen, Kuo, Calvin J., Sellers, Zachary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187319/
https://www.ncbi.nlm.nih.gov/pubmed/37205513
http://dx.doi.org/10.1101/2023.05.05.539132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187319/
https://www.ncbi.nlm.nih.gov/pubmed/37205513
http://dx.doi.org/10.1101/2023.05.05.539132

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