Combinatorial quantification of 5mC and 5hmC at individual CpG dyads and the transcriptome in single cells reveals modulators of DNA methylation maintenance fidelity

Transmission of 5-methylcytosine (5mC) from one cell generation to the next plays a key role in regulating cellular identity in mammalian development and diseases. While recent work has shown that the activity of DNMT1, the protein responsible for the stable inheritance of 5mC from mother to daughte...

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Detalles Bibliográficos
Autores principales: Chialastri, Alex, Sarkar, Saumya, Schauer, Elizabeth E., Lamba, Shyl, Dey, Siddharth S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187321/
https://www.ncbi.nlm.nih.gov/pubmed/37205524
http://dx.doi.org/10.1101/2023.05.06.539708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187321/
https://www.ncbi.nlm.nih.gov/pubmed/37205524
http://dx.doi.org/10.1101/2023.05.06.539708

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