Refinement of Multiconformer Ensemble Models from Multi-temperature X-ray Diffraction Data

Conformational ensembles underlie all protein functions. Thus, acquiring atomic-level ensemble models that accurately represent conformational heterogeneity is vital to deepen our understanding of how proteins work. Modeling ensemble information from X-ray diffraction data has been challenging, as t...

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Detalles Bibliográficos
Autores principales: Du, Siyuan, Wankowicz, Stephanie A., Yabukarski, Filip, Doukov, Tzanko, Herschlag, Daniel, Fraser, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187334/
https://www.ncbi.nlm.nih.gov/pubmed/37205593
http://dx.doi.org/10.1101/2023.05.05.539620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187334/
https://www.ncbi.nlm.nih.gov/pubmed/37205593
http://dx.doi.org/10.1101/2023.05.05.539620

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