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Randomized Trial of Ketamine Masked by Surgical Anesthesia in Depressed Patients

BACKGROUND: Ketamine may have antidepressant properties, but its acute psychoactive effects complicate successful masking in placebo-controlled trials. METHODS: In a triple-masked, randomized, placebo-controlled trial, 40 adult patients with major depressive disorder were randomized to a single infu...

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Detalles Bibliográficos
Autores principales: Lii, Theresa R., Smith, Ashleigh E., Flohr, Josephine R., Okada, Robin L., Nyongesa, Cynthia A., Cianfichi, Lisa J., Hack, Laura M., Schatzberg, Alan F., Heifets, Boris D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187335/
https://www.ncbi.nlm.nih.gov/pubmed/37205558
http://dx.doi.org/10.1101/2023.04.28.23289210