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Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory

The ability of monkeys and rats to carry out spatial working memory tasks has been shown to depend on the persistent firing of pyramidal cells in the prefrontal cortex (PFC), arising from recurrent excitatory connections on dendritic spines. These spines express hyperpolarization-activated cyclic nu...

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Detalles Bibliográficos
Autores principales: Wu, Jing, El-Hassar, Lynda, Datta, Dibyadeep, Thomas, Merrilee, Zhang, Yalan, Jenkins, David P., DeLuca, Nicholas J., Chatterjee, Manavi, Gribkoff, Valentin K., Arnsten, Amy F.T., Kaczmarek, Leonard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187370/
https://www.ncbi.nlm.nih.gov/pubmed/37205397
http://dx.doi.org/10.21203/rs.3.rs-2870277/v1