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Interaction Between HCN and Slack Channels Regulates mPFC Pyramidal Cell Excitability and Working Memory
The ability of monkeys and rats to carry out spatial working memory tasks has been shown to depend on the persistent firing of pyramidal cells in the prefrontal cortex (PFC), arising from recurrent excitatory connections on dendritic spines. These spines express hyperpolarization-activated cyclic nu...
Autores principales: | Wu, Jing, El-Hassar, Lynda, Datta, Dibyadeep, Thomas, Merrilee, Zhang, Yalan, Jenkins, David P., DeLuca, Nicholas J., Chatterjee, Manavi, Gribkoff, Valentin K., Arnsten, Amy F.T., Kaczmarek, Leonard K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187370/ https://www.ncbi.nlm.nih.gov/pubmed/37205397 http://dx.doi.org/10.21203/rs.3.rs-2870277/v1 |
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