Cargando…

Phase Separation in Mixtures of Prion-Like Low Complexity Domains is Driven by the Interplay of Homotypic and Heterotypic Interactions

Prion-like low-complexity domains (PLCDs) are involved in the formation and regulation of distinct biomolecular condensates that form via coupled associative and segregative phase transitions. We previously deciphered how evolutionarily conserved sequence features drive phase separation of PLCDs thr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pappu, Rohit, Farag, Mina, Borcherds, Wade, Bremer, Anne, Mittag, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187436/
https://www.ncbi.nlm.nih.gov/pubmed/37205474
http://dx.doi.org/10.21203/rs.3.rs-2870258/v1