Cargando…
Phase Separation in Mixtures of Prion-Like Low Complexity Domains is Driven by the Interplay of Homotypic and Heterotypic Interactions
Prion-like low-complexity domains (PLCDs) are involved in the formation and regulation of distinct biomolecular condensates that form via coupled associative and segregative phase transitions. We previously deciphered how evolutionarily conserved sequence features drive phase separation of PLCDs thr...
Autores principales: | Pappu, Rohit, Farag, Mina, Borcherds, Wade, Bremer, Anne, Mittag, Tanja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187436/ https://www.ncbi.nlm.nih.gov/pubmed/37205474 http://dx.doi.org/10.21203/rs.3.rs-2870258/v1 |
Ejemplares similares
-
Phase separation of protein mixtures is driven by the interplay of homotypic and heterotypic interactions
por: Farag, Mina, et al.
Publicado: (2023) -
Condensates formed by prion-like low-complexity domains have small-world network structures and interfaces defined by expanded conformations
por: Farag, Mina, et al.
Publicado: (2022) -
Deciphering how naturally occurring sequence features impact the phase behaviors of disordered prion-like domains
por: Bremer, Anne, et al.
Publicado: (2022) -
Quantifying Coexistence Concentrations in Multi-Component Phase-Separating Systems Using Analytical HPLC
por: Bremer, Anne, et al.
Publicado: (2022) -
Heterotypic and homotypic continuity in psychopathology: a narrative review
por: Speranza, Anna Maria, et al.
Publicado: (2023)