Molecular basis for GIGYF–TNRC6 complex assembly

The GIGYF proteins interact with 4EHP and RNA-associated proteins to elicit transcript-specific translational repression. However, the mechanism by which the GIGYF1/2–4EHP complex is recruited to its target transcripts remain unclear. Here, we report the crystal structures of the GYF domains from GI...

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Detalles Bibliográficos
Autores principales: Sobti, Meghna, Mead, Benjamin J., Stewart, Alastair G., Igreja, Cátia, Christie, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187677/
https://www.ncbi.nlm.nih.gov/pubmed/36854607
http://dx.doi.org/10.1261/rna.079596.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187677/
https://www.ncbi.nlm.nih.gov/pubmed/36854607
http://dx.doi.org/10.1261/rna.079596.123

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