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Molecular basis for GIGYF–TNRC6 complex assembly
The GIGYF proteins interact with 4EHP and RNA-associated proteins to elicit transcript-specific translational repression. However, the mechanism by which the GIGYF1/2–4EHP complex is recruited to its target transcripts remain unclear. Here, we report the crystal structures of the GYF domains from GI...
Autores principales: | Sobti, Meghna, Mead, Benjamin J., Stewart, Alastair G., Igreja, Cátia, Christie, Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187677/ https://www.ncbi.nlm.nih.gov/pubmed/36854607 http://dx.doi.org/10.1261/rna.079596.123 |
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