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Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer’s disease

A key challenge in developing diagnosis and treatments for Alzheimer’s disease (AD) is to detect abnormal network activity at as early a stage as possible. To date, behavioral and neurophysiological investigations in AD model mice have yet to conduct a longitudinal assessment of cellular pathology,...

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Detalles Bibliográficos
Autores principales: Zhang, Hai, Chen, Lujia, Johnston, Kevin G., Crapser, Joshua, Green, Kim N., Ha, Nicole My-Linh, Tenner, Andrea J., Holmes, Todd C., Nitz, Douglas A., Xu, Xiangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187684/
https://www.ncbi.nlm.nih.gov/pubmed/36462718
http://dx.doi.org/10.1016/j.nbd.2022.105939