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Osteoblastic Wls Ablation Protects Mice from Total Body Irradiation-Induced Impairments in Hematopoiesis and Bone Marrow Microenvironment

Ionizing irradiation (IR) causes bone marrow (BM) injury, with senescence and impaired self-renewal of hematopoietic stem cells (HSCs), and inhibiting Wnt signaling could enhance hematopoietic regeneration and survival against IR stress. However, the underlying mechanisms by which a Wnt signaling bl...

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Detalles Bibliográficos
Autores principales: Sim, Hyun-Jaung, So, Han-Sol, Poudel, Sher Bahadur, Bhattarai, Govinda, Cho, Eui-Sic, Lee, Jeong-Chae, Kook, Sung-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187694/
https://www.ncbi.nlm.nih.gov/pubmed/37191410
http://dx.doi.org/10.14336/AD.2022.1026