An integrated model for predicting KRAS dependency

The clinical approvals of KRAS G12C inhibitors have been a revolutionary advance in precision oncology, but response rates are often modest. To improve patient selection, we developed an integrated model to predict KRAS dependency. By integrating molecular profiles of a large panel of cell lines fro...

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Detalles Bibliográficos
Autores principales: Tsai, Yihsuan S., Chareddy, Yogitha S., Price, Brandon A., Parker, Joel S., Pecot, Chad V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187917/
https://www.ncbi.nlm.nih.gov/pubmed/37141389
http://dx.doi.org/10.1371/journal.pcbi.1011095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10187917/
https://www.ncbi.nlm.nih.gov/pubmed/37141389
http://dx.doi.org/10.1371/journal.pcbi.1011095

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