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7-Nitroindazole reduces L-DOPA-induced dyskinesias in non-human Parkinsonian primate

Nitric oxide (NO) plays a pivotal role in integrating dopamine transmission in the basal ganglia and has been implicated in the pathogenesis of Parkinson disease (PD). The objective of this study was to ascertain whether the NO synthase inhibitor, 7-nitroindazole (7-NI), is able to reduce L-DOPA-ind...

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Detalles Bibliográficos
Autores principales: Herrero, M. T., Yuste, J. E., Cuenca-Bermejo, L., Almela, P., Arenas-Betancur, L., De Pablos, V., Gonzalez-Cuello, A., Del Bel, E., Navarro-Zaragoza, J., Fernández-Villalba, E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188238/
https://www.ncbi.nlm.nih.gov/pubmed/37192671
http://dx.doi.org/10.1098/rsob.220370