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Recording of cellular physiological histories along optically readable self-assembling protein chains

Observing cellular physiological histories is key to understanding normal and disease-related processes. Here we describe expression recording islands—a fully genetically encoded approach that enables both continual digital recording of biological information within cells and subsequent high-through...

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Detalles Bibliográficos
Autores principales: Linghu, Changyang, An, Bobae, Shpokayte, Monika, Celiker, Orhan T., Shmoel, Nava, Zhang, Ruihan, Zhang, Chi, Park, Demian, Park, Won Min, Ramirez, Steve, Boyden, Edward S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188365/
https://www.ncbi.nlm.nih.gov/pubmed/36593405
http://dx.doi.org/10.1038/s41587-022-01586-7