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Ustekinumab Trough Concentrations Are Associated with Biochemical Outcomes in Patients with Crohn’s Disease

OBJECTIVE: It is unknown whether ustekinumab (UST) levels can predict clinical outcomes in Crohn’s disease (CD) patients. We assessed the exposure–response relationship of UST trough concentrations with biochemical outcomes at week 24 in a prospective, real-world setting. METHODS: We performed a pro...

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Detalles Bibliográficos
Autores principales: Straatmijer, Tessa, Biemans, Vince B. C., Moes, Dirk Jan A. R., Hoentjen, Frank, ter Heine, Rob, Maljaars, P. W. Jeroen, Theeuwen, Rosaline, Pierik, Marieke, Duijvestein, Marjolijn, van der Meulen-de Jong, Andrea E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188378/
https://www.ncbi.nlm.nih.gov/pubmed/36920666
http://dx.doi.org/10.1007/s10620-023-07822-7