Cargando…

IGH::CD274 (PD‐L1) rearrangement in diffuse large B cell lymphoma and its therapeutic implication

Diffuse large B cell lymphoma (DLBCL) expresses abundant programmed death ligand 1 (PD‐L1), which shields tumor cells from immune attacks through the PD‐L1/PD‐1 signaling axis. The mechanism of PD‐L1 overexpression includes the deletion of the 3′end of PD‐L1, which increases its mRNA stability, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xuemei, Chen, Si, Chen, Ping, Zhang, Han, Zhang, Liying, Wang, Panjun, Li, Bingzong, Rong, Rong, Wang, Yiting, Lang, Xingping, Wang, Kai, Zhang, Xiaohui, Xiao, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188474/
https://www.ncbi.nlm.nih.gov/pubmed/37206267
http://dx.doi.org/10.1002/jha2.693