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GDE7 produces cyclic phosphatidic acid in the ER lumen functioning as a lysophospholipid mediator

Cyclic phosphatidic acid (cPA) is a lipid mediator, which regulates adipogenic differentiation and glucose homeostasis by suppressing nuclear peroxisome proliferator-activated receptor γ (PPARγ). Glycerophosphodiesterase 7 (GDE7) is a Ca(2+)-dependent lysophospholipase D that localizes in the endopl...

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Detalles Bibliográficos
Autores principales:	Kitakaze, Keisuke, Ali, Hanif, Kimoto, Raiki, Takenouchi, Yasuhiro, Ishimaru, Hironobu, Yamashita, Atsushi, Ueda, Natsuo, Tanaka, Tamotsu, Okamoto, Yasuo, Tsuboi, Kazuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188492/ https://www.ncbi.nlm.nih.gov/pubmed/37193762 http://dx.doi.org/10.1038/s42003-023-04900-4

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