In situ-formable, dynamic crosslinked poly(ethylene glycol) carrier for localized adeno-associated virus infection and reduced off-target effects

The adeno-associated virus (AAV) is a potent vector for in vivo gene transduction and local therapeutic applications of AAVs, such as for skin ulcers, are expected. Localization of gene expression is important for the safety and efficiency of genetic therapies. We hypothesized that gene expression c...

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Detalles Bibliográficos
Autores principales: Kato, Motoi, Ishikawa, Shohei, Shen, Qi, Du, Zening, Katashima, Takuya, Naito, Mitsuru, Numahata, Takao, Okazaki, Mutsumi, Sakai, Takamasa, Kurita, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188511/
https://www.ncbi.nlm.nih.gov/pubmed/37193797
http://dx.doi.org/10.1038/s42003-023-04851-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188511/
https://www.ncbi.nlm.nih.gov/pubmed/37193797
http://dx.doi.org/10.1038/s42003-023-04851-w

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