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Excitatory somatostatin interneurons in the dentate gyrus drive a widespread seizure network in cortical dysplasia

Seizures due to cortical dysplasia are notorious for their poor prognosis even with medications and surgery, likely due to the widespread seizure network. Previous studies have primarily focused on the disruption of dysplastic lesions, rather than remote regions such as the hippocampus. Here, we fir...

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Detalles Bibliográficos
Autores principales: Zheng, Yang, Xu, Cenglin, Sun, Jinyi, Ming, Wenjie, Dai, Sijie, Shao, Yuying, Qiu, Xiaoyun, Li, Menghan, Shen, Chunhong, Xu, Jinghong, Fei, Fan, Fang, Jiajia, Jiang, Xuhong, Zheng, Guoqing, Hu, Weiwei, Wang, Yi, Wang, Shuang, Ding, Meiping, Chen, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188524/
https://www.ncbi.nlm.nih.gov/pubmed/37193687
http://dx.doi.org/10.1038/s41392-023-01404-9