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Single cell profiling at the maternal–fetal interface reveals a deficiency of PD-L1(+) non-immune cells in human spontaneous preterm labor

The mechanisms that underlie the timing of labor in humans are largely unknown. In most pregnancies, labor is initiated at term (≥ 37 weeks gestation), but in a signifiicant number of women spontaneous labor occurs preterm and is associated with increased perinatal mortality and morbidity. The objec...

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Detalles Bibliográficos
Autores principales: Liu, Xiao, Aneas, Ivy, Sakabe, Noboru, Anderson, Rebecca L., Billstrand, Christine, Paz, Cristina, Kaur, Harjot, Furner, Brian, Choi, Seong, Prichina, Adriana Y., Enninga, Elizabeth Ann L., Dong, Haidong, Murtha, Amy, Crawford, Gregory E., Kessler, John A., Grobman, William, Nobrega, Marcelo A., Rana, Sarosh, Ober, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188528/
https://www.ncbi.nlm.nih.gov/pubmed/37193763
http://dx.doi.org/10.1038/s41598-023-35051-5