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Lipidomics analysis facilitate insight into the molecular mechanisms of urate nephropathy in a gout model induced by combination of MSU crystals injection and high-fat diet feeding

Renal injury is one of the most common clinical manifestations of patients with hyperuricaemia/gout. The precise pathophysiological mechanism(s) for the renal injury is still unknown. Furthermore, it is also unclear whether the clinical therapies (e.g., colchicine and febuxostat) could prevent its p...

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Detalles Bibliográficos
Autores principales: Hao, Guifeng, Xu, Xiaofen, Song, Jingyi, Zhang, Jida, Xu, Kejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188924/
https://www.ncbi.nlm.nih.gov/pubmed/37206890
http://dx.doi.org/10.3389/fmolb.2023.1190683