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Alteration of gastric microbiota and transcriptome in a rat with gastric intestinal metaplasia induced by deoxycholic acid

OBJECTIVE: Bile reflux plays a key role in the development of gastric intestinal metaplasia (GIM), an independent risk factor of gastric cancer. Here, we aimed to explore the biological mechanism of GIM induced by bile reflux in a rat model. METHODS: Rats were treated with 2% sodium salicylate and a...

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Detalles Bibliográficos
Autores principales: Xu, Zijing, Xiao, Ling, Wang, Shuaishuai, Cheng, Yuqin, Wu, Jianping, Meng, Yufen, Bao, Kaifan, Zhang, Junfeng, Cheng, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188980/
https://www.ncbi.nlm.nih.gov/pubmed/37206332
http://dx.doi.org/10.3389/fmicb.2023.1160821