Substantiate a read-across hypothesis by using transcriptome data—A case study on volatile diketones

This case study explores the applicability of transcriptome data to characterize a common mechanism of action within groups of short-chain aliphatic α-, β-, and γ-diketones. Human reference in vivo data indicate that the α-diketone diacetyl induces bronchiolitis obliterans in workers involved in the...

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Detalles Bibliográficos
Autores principales: Drake, Christina, Wehr, Matthias M., Zobl, Walter, Koschmann, Jeannette, De Lucca, David, Kühne, Britta A., Hansen, Tanja, Knebel, Jan, Ritter, Detlef, Boei, Jan, Vrieling, Harry, Bitsch, Annette, Escher, Sylvia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188990/
https://www.ncbi.nlm.nih.gov/pubmed/37206915
http://dx.doi.org/10.3389/ftox.2023.1155645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10188990/
https://www.ncbi.nlm.nih.gov/pubmed/37206915
http://dx.doi.org/10.3389/ftox.2023.1155645

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