Effects of HLA single chain trimer design on peptide presentation and stability

MHC class I “single-chain trimer” molecules, coupling MHC heavy chain, β(2)-microglobulin, and a specific peptide into a single polypeptide chain, are widely used in research. To more fully understand caveats associated with this design that may affect its use for basic and translational studies, we...

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Detalles Bibliográficos
Autores principales: Finton, Kathryn A. K., Rupert, Peter B., Friend, Della J., Dinca, Ana, Lovelace, Erica S., Buerger, Matthew, Rusnac, Domnita V., Foote-McNabb, Ulysses, Chour, William, Heath, James R., Campbell, Jean S., Pierce, Robert H., Strong, Roland K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189100/
https://www.ncbi.nlm.nih.gov/pubmed/37207206
http://dx.doi.org/10.3389/fimmu.2023.1170462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189100/
https://www.ncbi.nlm.nih.gov/pubmed/37207206
http://dx.doi.org/10.3389/fimmu.2023.1170462

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