Cargando…
Effects of HLA single chain trimer design on peptide presentation and stability
MHC class I “single-chain trimer” molecules, coupling MHC heavy chain, β(2)-microglobulin, and a specific peptide into a single polypeptide chain, are widely used in research. To more fully understand caveats associated with this design that may affect its use for basic and translational studies, we...
Autores principales: | Finton, Kathryn A. K., Rupert, Peter B., Friend, Della J., Dinca, Ana, Lovelace, Erica S., Buerger, Matthew, Rusnac, Domnita V., Foote-McNabb, Ulysses, Chour, William, Heath, James R., Campbell, Jean S., Pierce, Robert H., Strong, Roland K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189100/ https://www.ncbi.nlm.nih.gov/pubmed/37207206 http://dx.doi.org/10.3389/fimmu.2023.1170462 |
Ejemplares similares
-
Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis
por: Heath, James, et al.
Publicado: (2022) -
Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis
por: Chour, William, et al.
Publicado: (2023) -
Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10
por: Finton, Kathryn A. K., et al.
Publicado: (2013) -
Mathematical modeling and biochemical analysis support partially ordered calmodulin-myosin light chain kinase binding
por: MacEwen, Melissa J.S., et al.
Publicado: (2023) -
Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor
por: Welcker, Markus, et al.
Publicado: (2022)