Hepatic myofibroblasts exert immunosuppressive effects independent of the immune checkpoint regulator PD-L1 in liver metastasis of pancreatic ductal adenocarcinoma

INTRODUCTION: Pancreatic ductal adenocarcinoma (PDAC) represents the 4(th) most common cause of cancer-related deaths in Western countries. Most patients are diagnosed at advanced stages, often already with metastases. The main site of metastasis is the liver and hepatic myofibroblasts (HMF) play a...

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Detalles Bibliográficos
Autores principales: Beckinger, Silje, Daunke, Tina, Aldag, Leon, Krüger, Sandra, Heckl, Steffen, Wesch, Daniela, Schäfer, Heiner, Röcken, Christoph, Rahn, Sascha, Sebens, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189124/
https://www.ncbi.nlm.nih.gov/pubmed/37207152
http://dx.doi.org/10.3389/fonc.2023.1160824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10189124/
https://www.ncbi.nlm.nih.gov/pubmed/37207152
http://dx.doi.org/10.3389/fonc.2023.1160824

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